BIOGRAPHICAL SKETCH
|
Biomedical Engineering
Department, Engineering Faculty, the University of Isfahan, HezarJerib.st. E-mail: m.mehdikhani@eng.ui.ac.ir Homepage: http://eng.ui.ac.ir/~m.mehdikhani/ |
|
NAME: Mehdikhani,
Mehdi
POSITION TITLE: Associate
Professor of Biomedical Engineering
EDUCATION/TRAINING
INSTITUTION
AND LOCATION |
DEGREE (if
applicable) |
Start Date MM/YYYY |
Completion Date MM/YYYY |
FIELD OF STUDY |
Isfahan
University of Technology, Isfahan, IRAN |
Ph.D. |
09/2005 |
02/2011 |
Biomaterials |
Isfahan
University of Technology, Isfahan, IRAN |
M.Sc. |
09/2001 |
02/2004 |
Materials
Engineering-Corrosion and Protection of Materials |
Islamic
Azad University, Najafabad , Isfahan, IRAN |
B.S |
09/1996 |
09/2000 |
Materials
Engineering |
A. Research Interest
My research is
focused on ‘Biomaterials for regenerative medicine and their use in drug
delivery systems. I am interested in developing biodegradable polymer-based
composites for bone, cartilage, skin, heart, nerve, ocular, and gastrointestinal
tract tissue engineering. Rational design and development of novel biodegradable
polymer scaffolds with customized properties tailored to deliver drugs in a
time-dependent manner to induce specific tissue regeneration is my considerable
interest. Furthermore, I am working on surface modification of the scaffolds to
improve cell interaction and enhanced properties in vivo.
B. Positions and Honors
2011-2014 Assistant Professor, Department of Materials Engineering, Faculty of Engineering, Semnan University, Semnan, IRAN
2014-2021 Assistant Professor, Department of Biomedical Engineering, Faculty of Engineering, University of Isfahan, Isfahan, IRAN.
2021- Ongoing Associate Professor, Department of Biomedical Engineering, Faculty of Engineering, University of Isfahan, Isfahan, IRAN.
Reviewer in the international journals
2014-Present Reviewer in the international journals (Materials Science & Engineering C, Journal of Medical Signals and Sensors, Dental Research Journal, Polymer Testing, Fibers and Polymers, etc.)
2015 Outstanding presentation in the idea festival in improving research at Isfahan University of
Medical Sciences
2012-2017 Iran National Science Foundation
2015-2017 Council for Stem Cell Sciences & Technologies
C. Contributions to Science
Published ISI papers in the research lines
21. Mehdikhani-Nahrkhalaji M, Fathi MH, Mortazavi V, Mousavi SB, Hashemi-Beni
B, Razavi SM, Novel poly (lactide-co-glycolide)/bioactive glass/hydroxyapatite nanocomposite
coating for dental applications. Materials Science: Materials in Medicine.
2012; 23: 485-495 (2012).
22. Mehdikhani-Nahrkhalaji M, Fathi MH, Mortazavi V, Mousavi SB, Razavi SM, Subcutaneous connective tissue reactions to the
three types of bioactive glass nanopowders. Journal
of Biomedical Nanotechnology. 2011; 7(3): 460-465.
23. Mortazavi V, Mehdikhani-Nahrkhalaji M, Fathi MH, Mousavi
SB, Nasr- Esfahani B, Antibacterial effects of
sol-gel derived bioactive glass nanoparticle on aerobic bacteria. Journal of
Biomedical Materials Research Part A. 2010; 94A: 160-168.
Selected
Published ISC and other papers
1.
Falak M, Mehdikhani M, Varshosaz J, Hashemibeni, Ebrahimian-Hosseinabadi
M, Fabrication and evaluation of spironolactone-loaded nanostructured lipid
carries for cardiac tissue regeneration, 10 (4); 2020: 260-265.
2.
Haghighat A, Mehdikhani-Nahrkhalaji M, Reihani A, Soltani-Dehnavi Sh, Eblaghian G. Novel
Chitosan/Polyethylene Glycol/Bioactive glass Nanocomposite membrane for Guided
Tissue/Bone Regeneration. International Journal of Advanced Biotechnology and
Research. 2017; 8(2): 787-800.
3.
Tavakoli E, Mehdikhani-Nahrkhalaji M, Sarafbidabad M. Poly (Lactic-co-Glycolic) Acid (PLGA)-Based
Compounds for Articular Cartilage Regeneration. Journal of Reports in
Pharmaceutical Sciences. 2016; 5(2): 94-103.
4.
Nazemi Z, Mehdikhani-Nahrkhalaji M, Haghbin Nazarpak M, Staji H. The antibacterial activity evaluation of sol-gel
prepared Zn-doped biphasic calcium phosphate nanopowders.
Advanced Science, Engineering and Medicine. 2015; 7: 995-1002.
5.
Mehdikhani-Nahrkhalaji M, Mohammad Hossein Fathi,
Vajihesadat Mortazavi, Sayed Behrouz Mousavi, Ali Akhavan, Abbas Haghighat, Batool
Hashemi-Beni, Sayed Mohammad Razavi, Fatemeh Mashadiabbas. Biocompatibility Evaluation of Biodegradable
Nanocomposite coatings for dental and orthopaedic
implant applications. Dental Research Journal. 2015; 12(1): 89-99.
6.
Mehdikhani-Nahrkhalaji M, Mohammad Hossein Fathi,Vajihesadat
Mortazavi, Sayed Behrouz Mousavi, Batool Hashemi-Beni, Sayed Mohammad Razavi, Ali Akhavan, Abbas Haghighat. In Vivo and In Vitro Evaluation of Poly
(lactide-co-glycolide)/Bioactive Glass Nanocomposite Coating.
Advanced Materials Research. 2014; 829: 309-313.
7.
Parsapour A, Fathi MH, Salehi M, Saatchi A, Mehdikhani
M. The Effect of Surface Treatment
on corrosion behavior of Surgical 316L Stainless Steel Implant. International
Journal of Iron & Steel Society of Iran. 2007; 4(1,2): 34-38.
8.
Selected
Conferences and Proceedings
1.
Shahravi Z, Mehdikhani M, Amirkhani Mohammad Amir, Farsaei
S, Molapour Sisakht Mahsa. Design of Novel Blend of Gellan
Gum / Polyvinyl Alcohol as Nano-fibrous Scaffold for Wound Dressings with
Appropriate Mechanical Properties, 4th International and 6th National Congress
of Wound and Tissue Repair, 2019 November
19, Iranian Society of Dermatology, Razi Hall,
Tehran, Iran.
2.
Mehdikhani M. New approaches to the tissue engineering. Symposium of application
of Biotechnology in Medical Science, 2018 April 13, Royan
Institute, Isfahan, Iran.
3.
Torabi H, Mehdikhani M. Injectable
hydrogels for myocardial tissue regeneration. The First International Iranian
Tissue Engineering and Regenerative Medicine Congress (ITERMC), 2018 July
18-20, Tehran, Iran.
4.
Ghaziof Sh,
Mehdikhani M. Renovaton of the injured
myocardial tssue with new conductve,
biodegradable, and non-cytotoxic
polymer matrix coated with fbrin glue nanocomposite
scaffold. Annual Biotechnology Congress, 2017 August 17-18, Toronto, Canada.
5.
Ghaziof Sh,
Mehdikhani-Nahrkhalaji M. New conductive nanocomposite
scaffold coated with fibrin glue for myocardial tissue engineering, Global
Congress on Tissue Engineering and Regenerative Medicine,2016 December 1-2, San
Antonio, USA.
6.
Ghaziof S, Mehdikhani-Nahrkhalaji M, Novel polycaprolactone/ Carbon nanotubes
nanocomposite scaffold for cardiac tissue engineering, 5th International
Conference on Tissue Engineering and Regenerative Medicine, 2016 September
12-14, Berlin, Germany.
7.
Mehdikhani-Nahrkhalaji M, Ghaziof
S. Preparation, Characterization, Mechanical,
and Electrical Conductivity Assessment of Novel Polycaprolactone / Multi Wall
Carbon Nanotubes Nanocomposites for Myocardial Tissue Engineering. 6th International
Advances in Applied Physics and Materials Science Congress & Exhibition
(APMAS2016), 2016 1-3 June, Steigenberger Hotel Maslak, Istanbul,Turkey.
8.
Sattari E, Hasanzadeh Nemati N, Mehdikhani-Nahrkhalaji M. Coating of mesoporous bioactive glass nanospheres
on stainless steel 316Lby sol-gel method. The First International Conference on
Science and Engineering, 2015, 1st of December, Dubai.
9.
Aghazadeh S, Hasanzadeh Nemati N, Mehdikhani-Nahrkhalaji M. Feassibility study
on application of mesoporous bioactive glass nanospheres as a filler of
cancerous bone defects. The First International Conference on Science and Engineering,
2015, 1st December, Dubai.
10. Reihany A, Mehdikhani-Nahrkhalaji
M, Haghighat A. Preparation and characterization of
chitosan-45S bioactive glass nanocomposite membrane for guided tissue regeneration.
26th European Students ’ Conference, 2015, 23-26 September, Berlin, Germany.
11. Aghazadeh S, Hasanzadeh Nemati N, Mehdikhani-Nahrkhalaji
M. The effect of calcium oxide in bioactive glass composition on the preparation
of spherical mesoporous nanoparticles for medical applications. The International
Conference on New Research in chemistry and Chemical Engineering, 2015, 17
September, Tehran, Iran.
12. Tavakoli E, Mehdikhani-Nahrkhlaji
M, Hashemi_beni B, Zargar-Kharazi
A. Preparation, Characterization, and mechanical assessment of Poly (Lactic-co-Glycolic)
Acid (PLGA) / Hyaluronic acid (Ha)/ Fibrin/ Bioactive glass Nano-composite
scaffolds for cartilage tissue engineering applications. the 5th international
conference on Ultrafine Grained and Nanostructured Materials, 2015, 11-12 November,
Tehran, Iran.
13. Khandan A,
Karamian E, Mehdikhani-Nahrkhalaji M, Mirmohammadi H, Farzadi A, Ozada N, Heidarshenas
B, Zamani K. Influence of Spark Plasma Sintering
and Baghdadite Powder on Mechanical Properties of Hydroxyapatite. 5th international
conference on Ultrafine Grained and Nanostructured Materials, 2015, 11-12
November, Tehran, Iran.
14. Raziye I, Mehdikhani-Nahrkhalaji
M, Karbasi S. Nanocomposites scaffold fabricated by
electrospinning for bone tissue engineering. International Congress on
Nanoscience & Nanotechnology 2014, 22-24 October, Tarbiat
Modares University, Tehran,Iran.
15. Nazemi Z, Mehdikhani-Nahrkhalaji
M, Haghbin-Nazarpak M. Synthesis and characterization
of Zn doped biphasic calcium phosphate nanoparticles prepared by sol-gel method.
International Congress on Nanoscience & Nanotechnology, 2014, 22-24 October,
Tarbiat Modares University,
Tehran,Iran.
16. Soltani-Dehnavi Sh, Mehdikhani-Nahrkhalaji M, Rafienia M, Doostmohammadi A. Antibacterial activity of sol-gel derived
copper-incorporated and copper free bioactive glass nanoparticles on a
gram-positive bacterium. 5th International Congress on Nanoscience &
Nanotechnology, 2014, 22-24 October, Tarbiat Modares University, Tehran, Iran.
17. Mehdikhani-Nahrkhalaji M, Fathi MH, Mortazavi
V. In vivo and In Vitro evaluation of poly (lactide-co-glycolide)/bioactive
glass nanocomposite coating in rabbit tibiae. 4th international conference on
Ultrafine Grained and Nanostructured Materials, 2013, Tehran University, Tehran,
Iran.
18. Mehdikhani-Nahrkhalaji M, Fathi MH, Mortazavi
V, Hashemi-Beni B. Poly (DL-lactide-co-glycolide)/
Bioactive glass nanocomposite coating for orthopedic and dental applications.
Proceedings of the 4th International Conference on Nanostructures, 2012, 12-14
March, Kish Island, I.R. Iran.
19. Mehdikhani-Nahrkhalaji M, Fathi MH,
Mortazavi V, Mousavi SB, Hashemi-Beni B. Poly (DL-lactide-co-glycolide)/ Bioactive Glass/Hydroxyapatite nanocomposite coating for dental implant
applications. The 6nd Annual Meeting of the IADR Iranian Division, Session Title:
Oral and Maxillofacial Surgery and Implantology, 2011, 29-30 December, Shahid
Beheshti University of Medical Sciences, Tehran, Iran.
20. Mehdikhani Nahrkhalaji M, Fathi MH,
Mortazavi V, Mousavi SB, Hashemi Beni B. Characterization and cytotoxicity
evaluation of poly (DL-lactide-co- glycolide)/bioactive
glass/hydroxyapatite nanocomposite coating on titanium, using human adipose
derived mesenchymal stem cell. Proceedings of the 3rd Conference on
Nanostructures, 2010, March 10-12, Kish Island, Iran.
21. Mehdikhani-Nahrkhalaji
M, Fathi MH, Mortazavi V, Mousavi SB, Razavi SM. Subcutaneous connective tissue reactions to the
three types of bioactive glass nanopowders. Diffusion
in Solids and Liquids Conference, 2010, 5-7 July, Paris, France.
22. Mortazavi V, Fathi MH, Mehdikhani Nahrkhalaji
M. Antibacterial effects of bioactive glass nanopowders
with different compositions. European Society for Artificial organs (ESAO),
2009, 2-5 September, Université de Technologie de Compiègne, , France, Sept 2-5, 2009.
23. Mehdikhani-Nahrkhalaji M, Fathi MH,
Mortazavi V, Mousavi SB. Preparation, characterization and bioactivity
evaluation of bioactive glass nano-powders with three different compositions.
New Materials National Congress, Materials and Energy Research Center, 2008,
10-12 June, Tehran, Iran.
Winning
National Projects:
1.
Mehdi Mehdikhani (PI), Mohammad Rafienia,
Shahin Bonakdar, Shiva Soltani-Dehnavi,
Ali Doostmohammadi, Preparation and characterization of
Polycaprolactone/Copper Doped Bioactive Glass Nanoparticles, The Office of
President, Vice-Presidency for Science and Technology, Iran National Science Foundation,
Start Date 06Apr2014 and End Date 16Dec2017.
2.
Mehdi Mehdikhani (PI), Anousheh Zargar Kharazi, Ebrahim Tavakoli, Fabrication,
Characterization, and Evaluation of Bioactivity and Mechanical Properties of
PLGA/FG/HA/nBG Nanocomposite Scaffold for Cartilage Tissue
Engineering Application and Investigating the Attachment and Viability of
Adipose Derived Mesenchymal Stem Cells on It, Start Date 04Apr2015 and End
Date 19Dec2017.
Books:
1.
Pharmaceutics: Drug Delivery and Targeting, Perrie,
Yvonne; Rades, Thomas, Second edition, Pharmaceutical
Press, 2012, Translated by Mehdi Mehdikhani, Ebrahim Tavakoli,
Bahjat Nafari, University
of Isfahan Press.
The
complete conference presentation list (http://eng.ui.ac.ir/~m.mehdikhani)
D.
Additional Information: Courses
YEAR |
COURSE TITLE |
MAJOR |
2011- |
Biocompatibility |
BME, M.Sc. |
2012- |
Physiology |
BME, B.S, M.Sc. |
2012- |
Anatomy |
BME, B.S, M.Sc. |
2011-2014 |
Tissue engineering |
BME, M.Sc. |
2011- |
Biological
experiments and sterilization methods |
BME, M.Sc. |
2012- |
Novel systems
for delivery of biologic materials |
BME, M.Sc. |
2013- |
Polymers and
their applications in biomedical engineering |
BME, M.Sc. |
2011- |
Ceramics and
their applications in biomedical engineering |
BME, M.Sc. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
2016- |
Specialized
English Language |
BME, M.Sc. |
BME: Biomedical Engineering
E.
Additional Information: Distinguished Researcher
Item |
Value |
Web
address |
ORCID |
0000-0002-6809-2891 |
https://orcid.org/0000-0002-6809-2891 |
Researcher ID |
B-1421-2018 |
http://www.researcherid.com/rid/B-1421-2018 |
Scopus Author ID |
36080960500 |
https://www.scopus.com/authid/detail.uri?authorId=36080960500 |
Google Scholar |
Mehdi Mehdikhani |
https://scholar.google.com/citations?user=KsaJoCUAAAAJ&hl=en |
Researchgate |
Mehdi Mehdikhani |
https://www.researchgate.net/profile/Mehdi_Mehdikhani |